Shirley D'Sa Selected Research

Complement C1s (C1 Esterase)

1/2022	Complement C1s inhibition with sutimlimab results in durable response in cold agglutinin disease: CARDINAL study 1-year interim follow-up results.
1/2020	Inhibition of complement C1s in patients with cold agglutinin disease: lessons learned from a named patient program.
1/2019	Inhibition of complement C1s improves severe hemolytic anemia in cold agglutinin disease: a first-in-human trial.

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Shirley D'Sa Research Topics

Disease

10	Autoimmune Hemolytic Anemia (Cold Agglutinin Disease) 01/2022 - 01/2019
8	Multiple Myeloma 12/2017 - 04/2003
6	Peripheral Nervous System Diseases (PNS Diseases) 01/2022 - 07/2011
5	Waldenstrom Macroglobulinemia (Macroglobulinemia) 01/2022 - 01/2018
4	Neoplasms (Cancer) 01/2022 - 04/2003
4	Lymphoma (Lymphomas) 01/2022 - 08/2005
4	Hemolysis 01/2022 - 01/2019
4	Paraproteinemias (Monoclonal Gammopathy) 01/2022 - 01/2015
4	POEMS Syndrome (Syndrome, POEMS) 01/2021 - 09/2018
3	Hypertension (High Blood Pressure) 01/2022 - 12/2020
3	Atrial Fibrillation 01/2022 - 10/2020
3	Fatigue 01/2022 - 07/2011
2	Monoclonal Gammopathy of Undetermined Significance 01/2022 - 10/2009
2	Pneumonia (Pneumonitis) 01/2022 - 10/2020
2	Diarrhea 01/2022 - 10/2020
2	Immunoglobulin Light-chain Amyloidosis 01/2022 - 01/2018
2	Hemolytic Anemia 11/2021 - 01/2019
2	Hemorrhage 12/2020 - 10/2020
2	Infections 10/2020 - 07/2011
2	Cranial Nerve Diseases (Cranial Nerve Disorders) 03/2016 - 03/2012
2	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 02/2016 - 10/2012
1	Meningitis 05/2022
1	Fever (Fevers) 01/2022
1	Headache (Headaches) 01/2022
1	Raynaud Disease (Raynaud's Disease) 01/2022
1	Rhinitis 01/2022
1	Sepsis (Septicemia) 01/2022
1	Schnitzler Syndrome 01/2022
1	Cryoglobulinemia 01/2022
1	Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) 01/2021
1	B-Cell Lymphoma (Lymphoma, B Cell) 11/2020
1	Spasm (Spasms) 10/2020
1	Contusions 10/2020
1	Neutropenia 10/2020
1	Edema (Dropsy) 10/2020
1	Disease Progression 02/2020
1	Pulmonary Embolism 01/2020
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2020
1	Long Term Adverse Effects 01/2020
1	Hypothyroidism 01/2019
1	Hypogonadism (Hypergonadotropic Hypogonadism) 01/2019
1	Adrenal Insufficiency (Adrenal Gland Hypofunction) 01/2019
1	Hyperprolactinemia 01/2019
1	Vasculitis (Vasculitides) 09/2018
1	Sleep Apnea Syndromes (Sleep Apnea) 09/2018
1	Anemia 09/2018
1	Chronic Obstructive Pulmonary Disease (COPD) 09/2018

Drug/Important Bio-Agent (IBA)

7	Immunoglobulin M (IgM)IBA 01/2022 - 01/2015
6	sutimlimabIBA 01/2022 - 01/2019
5	Rituximab (Mabthera)FDA Link 01/2022 - 03/2012
5	ibrutinibIBA 01/2022 - 10/2020
5	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2009
4	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2022 - 06/2005
4	Hemoglobins (Hemoglobin)IBA 01/2022 - 01/2019
4	Bortezomib (Velcade)FDA Link 01/2022 - 05/2013
3	Dexamethasone (Maxidex)FDA LinkGeneric 01/2022 - 06/2005
3	Agammaglobulinaemia Tyrosine KinaseIBA 01/2022 - 02/2020
3	zanubrutinibIBA 01/2022 - 10/2020
3	Complement C1s (C1 Esterase)IBA 01/2022 - 01/2019
2	SteroidsIBA 05/2022 - 05/2013
2	fludarabineIBA 01/2022 - 01/2020
2	Immunoglobulins (Immunoglobulin)IBA 01/2022 - 01/2021
2	BilirubinIBA 01/2021 - 01/2019
2	Complement System Proteins (Complement)IBA 01/2021 - 01/2019
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 09/2018
2	ParaproteinsIBA 01/2020 - 01/2018
2	Thalidomide (Thalomid)FDA Link 08/2012 - 06/2005
1	Phosphotransferases (Kinase)IBA 05/2022
1	MitogensIBA 05/2022
1	CryoglobulinsIBA 01/2022
1	Monoclonal AntibodiesIBA 01/2022
1	Immunoglobulin G (IgG)IBA 01/2022
1	Bendamustine Hydrochloride FDA Link 01/2022
1	Everolimus FDA Link 01/2022
1	AgglutininsIBA 11/2021
1	Enoxaparin (Lovenox)FDA LinkGeneric 12/2020
1	daratumumabIBA 07/2020
1	acalabrutinibIBA 02/2020
1	vinyltriethoxysilane (VTES)IBA 01/2020
1	Pharmaceutical PreparationsIBA 01/2019
1	Glucose (Dextrose)FDA LinkGeneric 01/2019
1	AntibodiesIBA 01/2019
1	HaptoglobinsIBA 01/2019
1	Insulin-Like Growth Factor I (IGF-1)IBA 01/2019
1	IronIBA 09/2018
1	4- (N- methylamino)- 4'- (2- (2- (2- fluoroethoxy)ethoxy)ethoxy)stilbeneIBA 01/2018
1	Biomarkers (Surrogate Marker)IBA 12/2017
1	6-bromo-2-naphthyl sulfate (BNS)IBA 03/2016
1	Lenalidomide (CC 5013)FDA Link 01/2015
1	Alkylating AgentsIBA 05/2013
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 10/2012

Therapy/Procedure

10	Therapeutics 12/2020 - 04/2003
4	Drug Therapy (Chemotherapy) 01/2022 - 04/2003
3	Stem Cell Transplantation 01/2022 - 10/2003
2	Transplantation 01/2022 - 04/2003
1	Drug Tapering 01/2022
1	Plasma Exchange 01/2022
1	Plasmapheresis 01/2022
1	Catheters 01/2020
1	Autologous Transplantation 01/2019